Immune Regulation Autoimmunity Tolerance Model
Product Code : JC-BE-6141
The Immune Regulation Autoimmunity Tolerance Model from Jaincolab is a three-dimensional teaching model that illustrates how the immune system maintains tolerance to self-antigens and what happens when that tolerance fails.
It is used in immunology and medical courses to explain central and peripheral tolerance, the role of regulatory T cells, and the mechanisms underlying autoimmunity.
What the Concept States
| Parameter | Details |
|---|---|
| Immune Tolerance | The ability of the immune system to avoid mounting a response against self-antigens |
| Central Tolerance | Elimination of self-reactive lymphocytes during development in the thymus and bone marrow |
| Peripheral Tolerance | Mechanisms that control self-reactive lymphocytes that escape central tolerance |
| Regulatory T Cells | Suppress self-reactive immune responses and help maintain peripheral tolerance |
| Anergy | Functional inactivation of lymphocytes that recognize self-antigen without proper co-stimulation |
| Autoimmunity | Breakdown of self-tolerance leading to immune attack on the body's own tissues |
Key Features
- Distinguishes central tolerance from peripheral tolerance
- Shows the role of regulatory T cells in maintaining self-tolerance
- Illustrates how tolerance breakdown leads to autoimmunity
- Durable, exam-oriented construction for repeated classroom use
- Compact benchtop format suitable for laboratories and lecture halls
Why Choose Jaincolab
Jaincolab (Jain Scientific Suppliers) is an ISO 9001:2015 and ISO 14001:2015 certified manufacturer and exporter of laboratory and scientific teaching models, supplying biology, chemistry, physics, and pharmacy equipment to institutions across India and internationally. Explore our complete range on the Biology Equipment category page, including our Hypersensitivity Reaction Model, for related immunology teaching aids.
Applications
| Application Area | Use |
|---|---|
| Immunology Education | Teaching immune tolerance mechanisms and their breakdown in disease |
| Medical Colleges | Correlating tolerance failure with autoimmune disorders |
| Biotechnology Training | Supporting coursework on regulatory T cell biology |
| Pathology Laboratories | Explaining autoimmune disease mechanisms |
| Science Exhibitions | Visual overview of immune tolerance and autoimmunity for general audiences |
Frequently Asked Questions
Q1. What does the Immune Regulation Autoimmunity Tolerance Model demonstrate?
A. It demonstrates how central and peripheral tolerance mechanisms prevent self-reactive immune responses, and how their failure leads to autoimmunity.
Q2. What is the difference between central and peripheral tolerance?
A. Central tolerance eliminates self-reactive lymphocytes during development, while peripheral tolerance controls self-reactive lymphocytes that escape into circulation.
Q3. What role do regulatory T cells play?
A. Regulatory T cells suppress self-reactive immune responses and help maintain peripheral tolerance.
Q4. What causes autoimmunity?
A. Autoimmunity arises when self-tolerance mechanisms break down, allowing the immune system to attack the body's own tissues.
Q5. Who uses this model?
A. Immunology, medical, and biotechnology students and faculty use it to study immune tolerance and autoimmunity.
Request a Quote
To request pricing or place an order for the Immune Regulation Autoimmunity Tolerance Model, please contact our team with your requirement.
