Telomerases Model
Product Code : JC-BE-6106
The Telomerases Model from Jaincolab is a three-dimensional teaching model that illustrates telomeres, the repetitive DNA sequences at the ends of chromosomes, and the role of the enzyme telomerase in maintaining them.
It is used in genetics, oncology, and medical courses to explain the end-replication problem, telomere shortening, and the link between telomerase activity, cellular aging, and cancer.
What the Concept States
| Parameter | Details |
|---|---|
| Telomeres | Repetitive DNA sequences that cap and protect the ends of chromosomes |
| End-Replication Problem | DNA polymerase cannot fully replicate the very ends of linear chromosomes, causing telomeres to shorten with each cell division |
| Telomerase | A reverse transcriptase enzyme that adds telomeric repeats to chromosome ends, counteracting telomere shortening |
| Telomerase RNA Template | An internal RNA component that telomerase uses as a template to synthesize new telomeric DNA |
| Cellular Aging | Progressive telomere shortening is linked to cellular senescence and aging |
| Cancer Relevance | Many cancer cells reactivate telomerase, allowing them to divide indefinitely |
Key Features
- Illustrates the end-replication problem and telomere shortening
- Shows how telomerase extends chromosome ends using its RNA template
- Links telomere biology to cellular aging and cancer
- Durable, exam-oriented construction for repeated classroom use
- Compact benchtop format suitable for laboratories and lecture halls
Why Choose Jaincolab
Jaincolab (Jain Scientific Suppliers) is an ISO 9001:2015 and ISO 14001:2015 certified manufacturer and exporter of laboratory and scientific teaching models, supplying biology, chemistry, physics, and pharmacy equipment to institutions across India and internationally. Explore our complete range on the Biology Equipment category page, including our DNA Replication Model, for related molecular biology teaching aids.
Applications
| Application Area | Use |
|---|---|
| Genetics Education | Teaching telomere structure and the end-replication problem |
| Oncology Training | Correlating telomerase reactivation with cancer cell immortality |
| Gerontology Research | Explaining the link between telomere shortening and cellular aging |
| Medical Colleges | Supporting coursework on molecular mechanisms of aging and cancer |
| Science Exhibitions | Visual overview of telomere and telomerase biology for general audiences |
Frequently Asked Questions
Q1. What does the Telomerases Model demonstrate?
A. It demonstrates the structure of telomeres, the end-replication problem, and how the enzyme telomerase extends telomeres to counteract shortening.
Q2. What is the end-replication problem?
A. It is the inability of DNA polymerase to fully replicate the very ends of linear chromosomes, which causes telomeres to shorten with each cell division.
Q3. How does telomerase work?
A. Telomerase is a reverse transcriptase enzyme that uses an internal RNA template to add new telomeric repeats to the ends of chromosomes.
Q4. Why are telomeres linked to cancer?
A. Many cancer cells reactivate telomerase, which prevents their telomeres from shortening and allows them to divide indefinitely.
Q5. Who uses this model?
A. Genetics, oncology, gerontology, and medical students and faculty use it to study telomere biology and telomerase activity.
Request a Quote
To request pricing or place an order for the Telomerases Model, please contact our team with your requirement.
