DNA Repair Mechanism Model
Product Code : JC-BE-6100
The DNA Repair Mechanism Model from Jaincolab is a three-dimensional teaching model that illustrates the major pathways cells use to correct damage to their DNA.
It is used in genetics, molecular biology, oncology, and medical courses to explain how mismatch repair, excision repair, and double-strand break repair pathways maintain genome stability.
What the Concept States
| Parameter | Details |
|---|---|
| Mismatch Repair | Corrects base-pairing errors that escape proofreading during DNA replication |
| Base Excision Repair | Removes and replaces a single damaged or incorrect base |
| Nucleotide Excision Repair | Removes a short stretch of nucleotides containing bulky DNA lesions, such as those caused by UV damage |
| Homologous Recombination | Repairs double-strand breaks using a matching DNA sequence as a template, restoring the original sequence |
| Non-Homologous End Joining | Repairs double-strand breaks by directly rejoining the broken ends, without using a template |
| Clinical Relevance | Defects in DNA repair pathways are linked to increased cancer risk and genetic instability |
Key Features
- Illustrates the major DNA repair pathways in a single reference model
- Distinguishes excision repair mechanisms from double-strand break repair
- Links DNA repair defects to cancer risk and genetic disease
- Durable, exam-oriented construction for repeated classroom use
- Compact benchtop format suitable for laboratories and lecture halls
Why Choose Jaincolab
Jaincolab (Jain Scientific Suppliers) is an ISO 9001:2015 and ISO 14001:2015 certified manufacturer and exporter of laboratory and scientific teaching models, supplying biology, chemistry, physics, and pharmacy equipment to institutions across India and internationally. Explore our complete range on the Biology Equipment category page, including our DNA Replication Model, for related molecular biology teaching aids.
Applications
| Application Area | Use |
|---|---|
| Genetics Education | Teaching the major pathways of DNA repair |
| Oncology Training | Correlating DNA repair defects with cancer development |
| Molecular Biology Laboratories | Explaining excision repair and double-strand break repair mechanisms |
| Medical Colleges | Supporting coursework on genome stability and genetic disease |
| Science Exhibitions | Visual overview of DNA repair for general audiences |
Frequently Asked Questions
Q1. What does the DNA Repair Mechanism Model demonstrate?
A. It demonstrates the major pathways, including mismatch repair, excision repair, and double-strand break repair, that cells use to correct DNA damage.
Q2. What is the difference between base excision repair and nucleotide excision repair?
A. Base excision repair removes a single damaged base, while nucleotide excision repair removes a short stretch of nucleotides containing a bulky lesion, such as UV-induced damage.
Q3. How are double-strand breaks repaired?
A. Double-strand breaks are repaired either by homologous recombination, using a matching DNA sequence as a template, or by non-homologous end joining, which directly rejoins the broken ends.
Q4. Why is DNA repair clinically important?
A. Defects in DNA repair pathways can lead to the accumulation of mutations and are linked to an increased risk of cancer and genetic instability.
Q5. Who uses this model?
A. Genetics, molecular biology, oncology, and medical students and faculty use it to study DNA repair mechanisms.
Request a Quote
To request pricing or place an order for the DNA Repair Mechanism Model, please contact our team with your requirement.
